| 货号 | 3353/50 |
| 别名 | 4-[5-(4-Butylcyclohexyl)-1,2,4-oxad |
| 供应商 | Tocris |
| 生物活性 | GPR119 receptor agonist (EC50 values are 8.4 and 7.9 μM at human and mouse receptors respectively). Displays similar potency to the endogenous ligand oleylethanolamide (OEA) (Cat. No. 1484). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 321.84 |
| 分子式 | C17H23N3O.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 388575-52-8 |
| 参考文献 | Ninget al (2008) Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on insulin secretion in MIN6c4 insulinoma cells. Br.J.Pharmacol. 155 1056. PMID: 18724386. Overtonet al (2006) Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. Cell Metab. 3 167. PMID: 16517404. |