| 货号 | 4410/50 |
| 别名 | 2-Pyridinyl[7-(4-pyridinyl)pyrazolo |
| 供应商 | Tocris |
| 生物活性 | Modulator of GABAA receptors. Displays modest selectivity for GABAAα1 receptors; displays partial agonist activity at α2-,α3- and α5-containing receptors. Exhibits anxiolytic activity. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 301.3 |
| 分子式 | C17H11N5O |
| 可溶性/溶解性 | Soluble to 100 mM in 2eq.HCl and to 10 mM in DMSO |
| 参考文献 | Mirzaet al (2006) Comparative cue generalization profiles of L-838,417, SL651498, zolpidem, CL218,872, ocinaplon, bretazenil, zopiclone, and various benzodiazepines in chlordiazepoxide and zolpidem drug discrimination. J.Pharmacol.Exp.Ther. 316 1291. PMID: 16339395. Rupprechtet al (2006) GABAA receptors as targets for novel anxiolytic drugs. World J.Biol.Psychiatry 7 231. PMID: 17071543. Lippaet al (2005) Selective anxiolysis produced by ocinaplon, a GABAA receptor modulator. Proc.Natl.Acad.Sci.USA 102 7380. PMID: 15870187. |