IQ 3 (50 MG)
货号：
4550/50 基本售价：
11381.8 元 规格：
50 mg
产品信息
概述| 货号 | 4550/50 |
| 别名 | 11H-Indeno[1,2-b]quinoxalin-11-one O-(2-furanylcarbonyl)oxime |
性能| 供应商 | Tocris |
| 生物活性 | Selective JNK3 inhibitor (Kd values are 66, 240 and 290 nM for JNK3, JNK1 and JNK2 respectively). Inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells (IC50 = 1.4 μM). Also inhibits TNF-α and IL-6 production in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 341.32 |
| 分子式 | C20H11N3O3 |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO |
| 参考文献 | Schepetkinet al (2012) Identification and characterization of a novel class of c-Jun N-terminal kinase inhibitors. Mol.Pharmacol. 81 832. PMID: 22434859. |
