iMDK (50 MG)
货号:
5126/50 基本售价:
11381.8 元 规格:
50 mg
产品信息
概述货号 | 5126/50 |
别名 | 3-[2-[(4-Fluorophenyl)methyl]imidazo[2,1-b]thiazol-6-yl]-2H-1-benzopyran-2-one |
性能供应商 | Tocris |
生物活性 | Suppressor of endogenous midkine (MDK) expression. Inhibits PI 3-K signaling in H441 lung adenocarcinoma cells. Selectively attenuates growth of MDK-expressing cancer cells. Induces apoptosis in H441 cells and suppresses growth of H441 cell xenografts in mice. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 376.4 |
分子式 | C21H13FN2O2< |
可溶性/溶解性 | Soluble to 5 mM in DMSO |
参考文献 | Haoet al (2013) Inhibition of the growth factor MDK/Midkine by a novel small molecule compound to treat non-small cell lung cancer. PLoS ONE 8 e71093. PMID: 23976985. |