| 货号 | 4870/50 |
| 别名 | 2,3-Dihydro-2-[3-(4-nitrophenoxy)ph |
| 供应商 | Tocris |
| 生物活性 | Antagonist of the lysophosphatidic acid receptors LPA1, LPA5 and LPA3(IC50 values are 94, 463 and 752 nM respectively). Exhibits no effect at LPA2 or LPA4receptors. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 404.33 |
| 分子式 | C21H12N2O7 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Fellset al (2010) 2D binary QSAR modeling of LPA3 receptor antagonism. J.Mol.Graph Model. 28 828. PMID: 20356772. Tigyi (2010) Aiming drug discovery at lysophosphatidic acid targets. Br.J.Pharmacol. 161 241. PMID: 20735414. Williamset al (2009) Unique ligand selectivity of the GPR92/LPA5 lysophosphatidate receptor indicates role in human platelet activation. J.Biol.Chem. 284 17304. PMID: 19366702. |