| 货号 | 3385/50 |
| 别名 | 2-[(3,4-Difluorophenyl)amino]-N-[2- |
| 供应商 | Tocris |
| 生物活性 | P2X7 allosteric modulator. Exhibits species-specific activity; acts as a negative allosteric modulator of human P2X7(pIC50 = 6.9 - 7.2) and a positive allosteric modulator of rat P2X7. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 483.81 |
| 分子式 | C20H24F2N4O.3HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| CAS号 | 1019779-04-4 |
| 参考文献 | Michelet al (2008) Negative and positive allosteric modulators of the P2X7 receptor. Br.J.Pharmacol. 153 737. PMID: 18071294. Michelet al (2008) Identification of regions of the P2X7 receptor that contribute to human and rat species differences in antagonist effects. Br.J.Pharmacol. 155 738. PMID: 18660826. |