货号 | 5694/50 |
别名 | 2,4,6-Trimethyl-N-[[3'-(methylsulfon |
供应商 | Tocris |
生物活性 | Potent LXR antagonist (pIC50 = 7.5). Enhances T-cell proliferation and blocks T 0901317-antiproliferative activity on T-cells. Cell permeable. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 591.66 |
分子式 | C29H28F3NO5< |
可溶性/溶解性 | Soluble to 20 mM in DMSO |
参考文献 | Soltet al (2012) LXR-mediated inhibition of CD4+ T helper cells. PLoS ONE 7 e46615. PMID: 23029557. Zuercheret al (2010) Discovery of tertiary sulfonamides as potent liver X receptor antagonists. J.Med.Chem. 53 3412. PMID: 20345102. |