货号 | 1658/50 |
别名 | 5-Fluoro-2-methoxy-[1-[2-[(methylsu |
供应商 | Tocris |
生物活性 | Potent and selective 5-HT4 receptor antagonist (Ki = 0.19 nM for porcine 5-HT4). Centrally active following systemic administration in vivo. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >97 % |
计算分子量 | 524.58 |
分子式 | C19H26FN3O5S.H2NSO3H |
可溶性/溶解性 | Soluble to 10 mM in water with gentle warming |
CAS号 | 144625-67-2 |
参考文献 | Horikoshiet al (2001) Possible involvement of 5-HT4 receptors, in addition to 5-HT3 receptors, in the emesis induced by high-dose cisplatin in Suncus murinus. Jpn.J.Pharmacol. 85 70. PMID: 11243577. Galeottiet al (1998) Role of 5-HT4 receptors in the mouse passive avoidance test. J.Pharmacol.Exp.Ther. 286 1115. PMID: 9732367. Schiaviet al (1994) Identification of serotonin 5-HT4 recognition sites in the porcine caudate nucleus by radioligand binding. Neuropharmacology 33 543. PMID: 7984293. |