EML 425 (50 MG)
货号：
5646/50 基本售价：
11381.8 元 规格：
50 mg
产品信息
概述| 货号 | 5646/50 |
| 别名 | 5-[(4-Hydroxy-2,6-dimethylphenyl)methylene]-1,3-bis(phenylmethyl)-2,4,6(1H,3H,5H)-pyrimidinetrione |
性能| 供应商 | Tocris |
| 生物活性 | Reversible and non-competitive CBP/p300 inhibitor (IC50 values are 1.1 and 2.9 μM, respectively). Cell permeable. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 440.49 |
| 分子式 | C27H24N2O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Militeet al (2015) A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach. J.Med.Chem. 58 2779. PMID: 25730130. |
