| 货号 | 1307/50 |
| 别名 | 5-[[4-[(1-Methylcyclohexyl)methoxy] |
| 供应商 | Tocris |
| 生物活性 | Selective agonist at PPARγ (peroxisome proliferator-activated receptor γ). Activates PPARγ with an EC50 value of 3 μMin vitro, and is at least 33-fold selective over PPARαandδ. Antihyperglycemic in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 333.44 |
| 分子式 | C18H23NO3S |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. NaOH |
| CAS号 | 74772-77-3 |
| 参考文献 | Jh (1999) Thiazolidinediones - the new insulin enhancers. Clin.Exp.Hypertens. 21 157. PMID: 10052651. Xinet al (1999) Peroxisome proliferator-activated receptor γ ligands are potent inhibitors of angiogenesis in vitroandin vivo. J.Biol.Chem. 274 9116. PMID: 10085162. Willsonet al (1996) The structure-activity relationship between peroxisome proliferator receptor γ agonism and the antihyperglycemic activity of thiazolidinediones. J.Med.Chem. 39 665. PMID: 8576907. |