| 货号 | 1114/50 |
| 别名 | 7-Chloro-5-(2-chlorophenyl)-1,5-dih |
| 供应商 | Tocris |
| 生物活性 | Selective antagonist of the mitochondrial Na+-Ca2+ exchanger (IC50 = 0.4 μM). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 324.22 |
| 分子式 | C15H11Cl2NOS |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 75450-34-9 |
| 参考文献 | Baron and Thayer (1997) CGP37157 modulates mitochondrial Ca2+ homeostasis in cultured rat dorsal root ganglion neurons. Eur.J.Pharmacol. 340 295. PMID: 9537826. White and Reynolds (1997) Mitochondria accumulate Ca2+ following intense glutamate stimulation of cultured rat forebrain neurones. J.Physiol. 498 31. PMID: 9023766. Coxet al (1993) Selectivity of inhibition of Na+-Ca2+ exchange of heart mitochondria by benzothiazepine CGP-37157. J.Cardiovasc.Pharmacol. 21 595. PMID: 7681905. Cox and Matlib (1993) Modulation of intramitochondrial free Ca2+ concentration by antagonists of Na+-Ca2+ exchange. TiPS 14 408. PMID: 8296399. |