货号 | 1082/50 |
别名 | 1-(4'-Aminophenyl)-3,5-dihydro-7,8-d |
供应商 | Tocris |
生物活性 | Novel, selective non-competitive AMPA antagonist. Highly potent, long-acting anticonvulsant. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 311.34 |
分子式 | C17H17N3O3 |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
CAS号 | 178616-26-7 |
参考文献 | De Sarroet al (1999) Effects of some AMPA receptor antagonists on the development of tolerance in epilepsy-prone rats and in pentylenetetrazole kindled rats. Eur.J.Pharmacol. 368 149. PMID: 10193651. De Sarroet al (1999) Anticonvulsant activity and plasma level of 2,3-benzodiazepin-4-ones (CFMs) in genetically epilepsy-prone rats. Pharmacol.Biochem.Behav. 63 621. PMID: 10462191. Chimirriet al (1997) 1-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: novel AMPA receptor antagonists. J.Med.Chem. 40 1258. PMID: 9111300. |