| 货号 | 1323/50 |
| 别名 | (2S)-[1-[(2S)-2-amino-1-oxobutyl]-N |
| 供应商 | Tocris |
| 生物活性 | Potent, reversible, selective and competitive inhibitor of a CCK-inactivating serine protease (tripeptidyl peptidase II) (Ki = 7 nM). Active in vivo(ID50 = 1.1 and 6.8 mg/kg i.v. for inhibition of liver and brain enzyme respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >99 % |
| 计算分子量 | 393.44 |
| 分子式 | C17H25N3O2.C2H2O4 |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| CAS号 | 175553-48-7 |
| 参考文献 | Ganellinet al (2000) Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J.Med.Chem. 43 664. PMID: 10691692. Rennet al (1998) Characterization and cloning of tripeptidyl peptidase II from the fruit fly, Drosophila melanogaster. J.Biol.Chem. 273 19173. PMID: 9668104. Roseet al (1996) Characterization and inhibition of a cholecystokinin-inactivating serine peptidase. Nature 380 403. PMID: 8602240. |