| 货号 | 1442/50 |
| 别名 | [3-(4,5-Diphenyl[2,4'-bioxazol]-5'-yl |
| 供应商 | Tocris |
| 生物活性 | Non-prostanoid prostacyclin mimetic that acts as a partial agonist at IP1 prostacyclin receptors. Potently inhibits platelet aggregation in vitro(IC50 = 27-35 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 438.44 |
| 分子式 | C26H18N2O5 |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO |
| CAS号 | 152575-66-1 |
| 参考文献 | Ruddet al (2000) Non-prostanoid prostacyclin mimetics as neuronal stimulants in the rat: comparison of vagus nerve and NANC innervation of the colon. Br.J.Pharmacol. 129 782. PMID: 10683203. Seileret al (1997) [3-[4-(4,5-Diphenyl-2-oxazolyl)-5-oxazolyl]phenoxy]acetic acid (BMY 45778) is a potent non-prostanoid prostacyclin partial agonist: effects on platelet aggregation, adenylyl cyclase, cAMP levels, protein kinase, and iloprost binding. Prostaglandins 53 21. PMID: 9068064. Meanwellet al (1993) Nonprostanoid prostacyclin mimetics. 5. Structure-activity relationships associated with [3-[4-(4,5-diphenyl-2-oxazolyl)-5-oxazolyl]phenoxy]acetic acid. 36 3884. PMID: 7504734. |