货号 | 3509/50 |
别名 | 4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl |
供应商 | Tocris |
生物活性 | Pan-retinoic acid receptor (pan-RAR) inverse agonist. Enhances nuclear corepressor (NCoR) interaction with RARs. Binding induces analogous conformational changes in all RAR types (RARα, RARβ and RARγ). |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 404.5 |
分子式 | C29H24O2 |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
CAS号 | 215030-90-3 |
参考文献 | Germainet al (2009) Differential action on coregulator interaction defines retinoid agonists and neutral antagonists. Chem.Biol. 16 479. PMID: 19477412. Rinkevichet al (2007) Systemic bud induction and retinioic acid signaling underlie whole body regeneration in the urochordate Botrylloides leachi. PLoS Biology. 5 e71. PMID: 17341137. |