Bazedoxifene acetate (50 MG)
货号：
5263/50 基本售价：
11381.8 元 规格：
50 mg
产品信息
概述| 货号 | 5263/50 |
| 别名 | 1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol acetate |
性能| 供应商 | Tocris |
| 生物活性 | Potent selective estrogen receptor modulator (SERM) (IC50 values are 26 and 99 nM for ERα and ERβ respectively). Inhibits 17β-estradiol-induced proliferation in MCF-7 cells. Co-treatment with Raloxifene (Cat No. 2280) completely abolishes raloxifene-induced stimulation of luminal epithelial cells and myometrium. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 530.65 |
| 分子式 | C30H34N2O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
| 参考文献 | Kommet al (2005) Bazedoxifene acetate: a selective estrogen receptor modulator with improved selectivity. Endocrinology 146 3999. PMID: 15961563. |
