BAM 7 (50 MG)
货号:
4810/50 基本售价:
11381.8 元 规格:
50 mg
产品信息
概述货号 | 4810/50 |
别名 | 3-Methyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione 4-[2-(2-Ethoxyphenyl)hydrazone] |
性能供应商 | Tocris |
生物活性 | Bax activator (EC50 = 3.3 μM); binds at the BH3-binding site. Selective for Bax over other antiapoptotic and proapoptotic proteins. Triggers Bax oligomerization in vitro; induces Bax-mediated apoptosis in mouse embryonic fibroblasts. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 405.47 |
分子式 | C21H19N5O2 |
可溶性/溶解性 | Soluble to 10 mM in DMSO |
参考文献 | Gavathiotiset al (2012) Direct and selective small-molecule activation of proapoptotic BAX. Nat.Chem.Biol. 8 639. PMID: 22634637. |