货号 | 1968/50 |
别名 | (2S)-(+)-5-(1,3,5-Trimethylpyrazol- |
供应商 | Tocris |
生物活性 | Potent 5-HT7 receptor agonist (IC50 = 0.83 nM). Enhances memory consolidation and reverses scopolamine- or dizocilpine-induced amnesia in vivo. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 283.41 |
分子式 | C18H25N3 |
可溶性/溶解性 | Soluble to 100 mM in ethanol and to 100 mM in DMSO |
参考文献 | Horiguchiet al (2011) The role of 5-hydroxytrpytamine 7 receptors in the phencyclidine-induced novel object recognition deficit in rats. J.Pharmacol.Exp.Ther. 338 605. PMID: 21558435. Perez-Garciaet al (2006) An mRNA expression analysis of stimulation and blockade of 5-HT7 receptors during memory consolidation. Behav.Brain Res. 169 83. PMID: 16480781. Perez-Garcia and Meneses (2005) Effects of the potential 5-HT7 receptor agonist AS 19 in an autoshaping learning task. Behav.Brain Res. 163 136. PMID: 15936093. |