AGK 2 (50 MG)
货号：
3233/50 基本售价：
11381.8 元 规格：
50 mg
产品信息
概述| 货号 | 3233/50 |
| 别名 | 2-Cyano-3-[[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide |
性能| 供应商 | Tocris |
| 生物活性 | Selective inhibitor of SIRT2 (IC50 = 3.5 μM). Displays no activity at SIRT1 and SIRT3 at concentrations up to 40 μM. Reduces α-synuclein-mediated toxicity in in vitroandin vivo models of Parkinson's disease. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 434.27 |
| 分子式 | C23H13Cl2N3O2 |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO |
| CAS号 | 304896-28-4 |
| 参考文献 | Outeiroet al (2007) Sirtuin 2 inhibitors rescue α-synuclein-mediated toxicity in models of Parkinson's disease. Science 317 516. PMID: 17588900. |
