货号 | 4046/50 |
别名 | 4-[4-(2-Butoxyethoxy-)-5-methyl-2-t |
供应商 | Tocris |
生物活性 | Potent RARβ2 agonist (pEC50 = 8.1). Selective over RARβ1, RARα and RARγ(pEC50 values are 6.4, 6.2 and 6.3 respectively). More potent and orally available than AC 55649 (Cat. No. 2436). |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 353.41 |
分子式 | C17H20FNO4S |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
CAS号 | 870773-76-5 |
参考文献 | Lundet al (2009) Design, synthesis, and structure-activity analysis of isoform-selective retinoic acid receptor β ligands. J.Med.Chem. 52 1540. PMID: 19239230. Lundet al (2005) Discovery of a potent, orally available, and isoform-selective retinoic acid β2 receptor agonist. J.Med.Chem. 48 7517. PMID: 16302793. |