A 484954 (50 MG)
货号：
4483/50 基本售价：
11381.8 元 规格：
50 mg
产品信息
概述| 货号 | 4483/50 |
| 别名 | 7-Amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide |
性能| 供应商 | Tocris |
| 生物活性 | Inhibitor of eukaryotic elongation factor-2 (eEF-2) kinase (IC50 = 0.28 μM in enzymatic assay). Reduces eEF-2 phosphorylation with little effect on cancer cell growth. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 289.29 |
| 分子式 | C13H15N5O3 |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO |
| 参考文献 | Chenet al (2011) 1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125) induces phosphorylation of eukaryotic elongation factor-2 (eEF2): a cautionary note on the anticancer mechanism of an eEF2 kinase inhibitor. J.Biol.Chem. 286 43951. PMID: 22020937. |
