Lipoxin B4
货号：
90420-100ug 基本售价：
11284.0 元 规格：
100 ug
产品信息
概述| 货号 | 90420-100ug |
| 描述 | Lipoxins are a series of anti-inflammatory lipid mediators whose brief appearance generally signals the resolution of inflammation. Lipoxin A4(LXA4) is a potent inhibitor of leukotriene (LT)-triggered polymorphonuclear neutrophil (PMN)-endothelial cell interaction and also blocks PMN migration stimulated by LTB4. LXB4 is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes.1,2 At a concentration of 10-7 M, LXB4 inhibits PMN migration stimulated by LTB4 and inhibits LTB4-induced adhesion of PMNs with an IC50 value of ~3 X 10-10 M.3 |
| 别名 | LXB4; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Serhan, C.N.,Hamberg, M.,Samuelsson, B., et al. On the stereochemistry and biosynthesis of lipoxin B. Proceedings of the National Academy of Sciences of the United States of America 83, 1983-1987 (1986).
2.Serhan, C.N.,Hamberg, M. and Samuelsson, B. Lipoxins: Novel series of biologically active compounds formed from arachidonic acid in human leukocytes. Proceedings of the National Academy of Sciences of the United States of America 81, 5335-5339 (1984).
3.Papayianni, A.,Serhan, C.N. and Brady, H.R. Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells. Journal of Immunology 156, 2264-2272 (1996).
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| 运输条件 | Dry ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 纯度 | ≥95% |
| 计算分子量 | 352.5 |
| 分子式 | C20H32O5 |
| CAS号 | 98049-69-5 |
| 稳定性 | ≥ 1 year |
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