CAY10397
货号：
70130-25mg 基本售价：
11270.0 元 规格：
25 mg
产品信息
概述| 货号 | 70130-25mg |
| 描述 | Prostaglandins are rapidly inactivated in vivo by the action of 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH). This enzyme oxidizes the 15-hydroxyl group and hydrogenates the 13,14-double bond, producing 13,14-dihydro-15 keto metabolites with greatly reduced biological activity. CAY10397 is a selective inhibitor of 15-hydroxy PGDH with an IC50 of approximately 10 µM.1 CAY10397 acts to prolong the lifetime and activity of endogenously produced prostaglandins both in cell culture and in vivo. |
| 别名 | CK47A; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Berry, C.N.,Hoult, J.R.S.,Peers, S.H., et al. Inhibition of prostaglandin 15-hydroxydehydrogenase by sulphasalazine and a novel series of potent analogues. Biochemical Pharmacology 32, 2863-2871 (1983).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 328.3 |
| 分子式 | C17H16N2O5 |
| CAS号 | 78028-01-0 |
| 稳定性 | ≥ 1 year |
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