WWL 113 (50 MG)
货号：
5259/50 基本售价：
11233.1 元 规格：
50 mg
产品信息
概述| 货号 | 5259/50 |
| 别名 | 4'-[[[Methyl[[3-(4-pyridinyl)phenyl]methyl]amino]carbonyl]oxy]-[1,1'-biphenyl]-4-carboxylic acid ethyl ester |
性能| 供应商 | Tocris |
| 生物活性 | Carboxylesterase Ces3 and Ces1f inhibitor (IC50 values are ~100 nM). Also inhibits ABHD6. Exhibits minimal activity against a panel of other serine hydrolases. Promotes lipid storage in adipocytes. Reduces weight gain in diet-induced obese mice and enhances glucose tolerance in diabetic mice. Orally active. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >99 % |
| 计算分子量 | 466.53 |
| 分子式 | C29H26N2O4 |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO |
| 参考文献 | Dominguezet al (2014) Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes. Nat.Chem.Biol. 10 113. PMID: 24362705. |
