UNC 3230 (50 MG)
货号：
5271/50 基本售价：
11233.1 元 规格：
50 mg
产品信息
概述| 货号 | 5271/50 |
| 别名 | 5-[(Cyclohexylcarbonyl)amino]-2-(phenylamino)-thiazolecarboxamide |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective PIP5K1C inhibitor (IC50 = 41 nM). Exhibits selectivity for PIP5K1C over PIP5K1A, the PI 3-kinase family and a panel of other kinases. Reduces PIP2 levels and LPA-induced calcium signaling in dorsal root ganglia (DRG) neurons in vitro. Reduces nociception in mouse models of chronic pain. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 344.43 |
| 分子式 | C17H20N4O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Wrightet al (2014) The lipid kinase PIP5K1C regulates pain signaling and sensitization. Neuron 82 836. PMID: 24853942. |
