SGC 707 (50 MG)
货号：
5367/50 基本售价：
11233.1 元 规格：
50 mg
产品信息
概述| 货号 | 5367/50 |
| 别名 | 1-(Isoquinolin-6-yl)-3-[2-oxo-2-(pyrrolidin-1-yl)ethyl] urea |
性能| 供应商 | Tocris |
| 生物活性 | Potent allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50 = 31 nM). Inhibits PRMT3-mediated methyltransferase activity in vitro. Displays >100-fold selectivity against 31 other methyltransferases and 250 other non-epigenetic targets. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 298.34 |
| 分子式 | C16H18N4O2 |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO |
| 参考文献 | Kaniskanet al (2015) A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3). Angew.Chem.Int.Ed.Engl 54 5166. PMID: 25728001. |
