| 货号 | 1982/50 |
| 别名 | (2R*)-2-[(R*)-(2-Ethoxyphenoxy)phen |
| 供应商 | Tocris |
| 生物活性 | Potent and selective inhibitor of noradrenalin uptake (Ki values are 1.1, 129 and > 10000 nM for rat NET, SERT and DAT respectively). Displays > 1000-fold selectivity over α-adrenoceptors, 5-HT, dopamine and muscarinic ACh receptors. Orally active antidepressant. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 409.5 |
| 分子式 | C19H23NO3.CH3SO3H |
| 可溶性/溶解性 | Soluble to 50 mM in water and to 50 mM in DMSO |
| CAS号 | 71620-89-8 |
| 参考文献 | Owen and Whitton (2003) Reboxetine modulates norepinephrine efflux in the frontal cortex of the freely moving rat: the involvement of α2 and 5-HT1A receptors. Neurosci.Lett. 348 171. PMID: 12932821. Millanet al (2001) S33005, a novel ligand at both serotonin and norepinephrine transporters: I Receptor binding, electrophysiological, and neurochemical profile in comparison with venlafaxine, reboxetine, citalopram, and clomipramine. J.Pharmacol.Exp.Ther. 298 565. PMID: 11454918. Wonget al (2000) Reboxetine: a pharmacologically potent, selective, and specific norepinephrine reuptake inhibitor. Biol.Psychiatry. 47 818. PMID: 10812041. Sacchettiet al (1999) Studies on the acute and chronic effects of reboxetine on extracellular noradrenaline and other monoamines in the rat brain. Br.J.Pharmacol. 128 1332. PMID: 10578149. |