| 货号 | 1199/50 |
| 别名 | 8,8'-[Carbonylbis(imino-4,1-phenylen |
| 供应商 | Tocris |
| 生物活性 | A potent and selective P2X1 antagonist (IC50 = 19 nM). Displays good selectivity over P2X2,(IC50 = 0.76 μM), P2X3(IC50 = 1.62μM), P2X4(IC50 > 300 μM), P2Y receptors and ecto-nucleotidases. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1401.1 |
| 分子式 | C49H30N6Na6O23S6 |
| 可溶性/溶解性 | Soluble to 25 mM in water |
| CAS号 | 202983-32-2 |
| 参考文献 | Klapperstucket al (2000) Antagonism by the suramin analogue NF 279 on human P2X1 and P2X7 receptors. Eur.J.Pharmacol. 387 245. PMID: 10650169. Rettingeret al (2000) The suramin analogue NF279 is a novel and potent antagonist selective for the P2X1 receptor. Neuropharmacology 39 2044. PMID: 10963748. Dameret al (1998) NF279: a novel potent and selective antagonist of P2X receptor-mediated responses. Eur.J.Pharmacol. 350 R5. PMID: 9683026. |