MNI 137 (50 MG)
货号：
4388/50 基本售价：
11233.1 元 规格：
50 mg
产品信息
概述| 货号 | 4388/50 |
| 别名 | 4-(8-Bromo-2,3-dihydro-2-oxo-1H-1,5-benzodiazepin-4-yl)-2-pyridinecarbonitrile |
性能| 供应商 | Tocris |
| 生物活性 | Selective negative allosteric modulator of group II mGlu receptors (IC50 values are 8.3 and 12.6 nM for human and rat mGlu2 inhibition of glutamate-induced calcium mobilization). Displays no activity at mGlu1, mGlu4, mGlu5 or mGlu8 receptors in a calcium mobilization assay. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 341.16 |
| 分子式 | C15H9BrN4O |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO |
| 参考文献 | Hemstapatet al (2007) A novel family of potent negative allosteric modulators of group II metabotropic glutamate receptors. J.Pharmacol.Exp.Ther. 322 254. PMID: 17416742. |
