| 货号 | 0103/50 |
| 别名 | L-(+)-2-Amino-4-phosphonobutyric acid |
| 供应商 | Tocris |
| 生物活性 | Selective group III metabotropic glutamate receptor agonist. Synaptic depressant. Agonist at the quisqualate-sensitized AP6 site in hippocampus. Also available as part of the Group III mGlu Receptor Tocriset™ and Mixed mGlu Receptor Tocriset™. DL Mixture (Cat. No. 0101) and D-isomer (Cat. No. 0102) also available. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 183.1 |
| 分子式 | C4H10NO5P |
| 可溶性/溶解性 | Soluble to 5 mM in water and to 100 mM in 1eq. NaOH |
| CAS号 | 23052-81-5 |
| 参考文献 | Bushellet al (1995) Antagonism of the synaptic depressant actions of L-AP4 in the lateral perforant path by MAP4. Neuropharmacology 34 239. PMID: 7617150. Toneset al (1995) The agonist selectivity of a class III metabotropic glutamate receptor, human mGluR4a, is determined by the N-terminal extracellular domain. NeuroReport 7 117. PMID: 8742431. Nakanishi (1992) Molecular diversity of glutamate receptors and implications for brain functions. Science 258 597. PMID: 1329206. Evanset al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75 65. PMID: 7042024. |