ETP 45835 dihydrochloride (50 MG)
货号:
5183/50 基本售价:
11233.1 元 规格:
50 mg
产品信息
概述货号 | 5183/50 |
别名 | 4-[5-(4-Piperidinyl)-1H-pyrazol-3-yl]pyridine dihydrochloride |
性能供应商 | Tocris |
生物活性 | Mnk2 and Mnk1 inhibitor (IC50 values are 575 and 646 nM respectively). Exhibits selectivity against a panel of 24 protein kinases, including those upstream of Mnk1/2. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 301.21 |
分子式 | C13H16N4.2HCl |
可溶性/溶解性 | Soluble to 100 mM in water |
参考文献 | Oyarzabalet al (2010) Discovery of mitogen-activated protein kinase-interacting kinase 1 inhibitors by a comprehensive fragment-oriented virtual screening approach. J.Med.Chem. 53 6618. PMID: 20722422. |