| 货号 | 5164/50 |
| 别名 | 3-[[[3-[4-[(Methylsulfonyl)amino]ph |
| 供应商 | Tocris |
| 生物活性 | Potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50 values are 29 and 1300 nM for ALDH2 and ALDH1, respectively). Exhibits anxiolytic effects in rat models. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 465.48 |
| 分子式 | C24H19NO7S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in 1eq. NaOH |
| 参考文献 | Yaoet al (2010) Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use-dependent inhibitor of dopamine synthesis. Nat.Med. 16 1024. PMID: 20729865. Overstreetet al (2009) A selective ALDH-2 inhibitor reduces anxiety in rats. Pharmacol.Biochem.Behav. 94 255. PMID: 19747934. |