| 货号 | 3410/50 |
| 别名 | 3-Fluoro-4-[[2-hydroxy-2-(5,5,8,8-t |
| 供应商 | Tocris |
| 生物活性 | Selective RARγ agonist (EC50 values are 30 and 1000 nM at RARγ and RARβ respectively). Displays no activity at RARαreceptors. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >97 % |
| 计算分子量 | 399.46 |
| 分子式 | C23H26FNO4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Klaholzet al (2000) Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARγ. Proc.Natl.Acad.Sci. 976322. Abu-Abedet al (1998) Mouse P450RAI (CYP26) expression and retinoic acid-inducible retinoic acid metabolism in F9 cells are regulated by retinoic acid receptor γ and retinoid X receptor α. J.Biol.Chem. 273 2409. PMID: 9442090. Tanejaet al (1996) Cell-type and promoter-context dependent retinoic acid receptor (RAR) redundancies for RARβ2andHoxa-1 activation in F9 and P19 cells can be artefactually generated by gene knockouts. Proc.Natl.Acad.Sci.USA 936197. |