| 货号 | 16528-5mg |
| 描述 | Spinosyn A is a naturally-occurring macrocyclic lactone that is a potent insecticide.1,2 It acts as an agonist of insect nicotinic acetylcholinesterase receptors (nAChRs), which differ both structurally and functionally from nAChRs in vertebrates.3 As a result, it has low affinity for vertebrate nAChRs and has limited adverse effects in those animals.3,4 Spinosyn A is produced naturally by the fermentation of the bacterium S. spinosa and its chemical synthesis has been described.5 |
| 别名 | A-83543A;Lepicidin A; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Creemer, L.C.,Kirst, H.A.,Paschal, J.W., et al. Synthesis and insecticidal activity of spinosyn analogs functionally altered at the 2-,3- and 4-positions of the rhamnose moiety. J.Antibiot.(Tokyo) 53(2), 171-178 (2000). 2.Duke, S.O.,Cantrell, C.L.,Meepagala, K.M., et al. Natural toxins for use in pest management. Toxins (Basel) 2(8), 1943-1962 (2010). 3.Vo, D.T.,Hsu, W.H.,Abu-Basha, E.A., et al. Insect nicotinic acetylcholine receptor agonists as flea adulticides in small animals. Journal of Veterinary Pharmacology and Therapeutics 33(4), 315-322 (2010). 4.Amaral, T.S.,Carvalho, T.F.,Silva, M.C., et al. Short-term effects of a spinosyn’s family insecticide on energy metabolism and liver morphology in frugivorous bats Artibeus lituratus (Olfers, 1818). Braz.J.Biol. 72(2), 299-304 (2012). 5.Mergott, D.J.,Frank, S.A. and Roush, R.W. Total synthesis of (−)-spinosyn A. Proceedings of the National Academy of Sciences of the United States of America 101(33), 11955-11959 (2004). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% |
| 计算分子量 | 732 |
| 分子式 | C41H65NO10 |
| CAS号 | 131929-60-7 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |