NI 42 ( )
货号：
5786/50 基本售价：
11084.4 元 规格：
50 mg
产品信息
概述| 货号 | 5786/50 |
| 别名 | 4-Cyano-N-(1,2-dihydro-1,3-dimethyl-2-oxo-6-quinolinyl)benzenesulfonamide |
性能| 供应商 | Tocris |
| 生物活性 | High affinity BRPF inhibitor (Kd values are 40, 210 and 943 nM for BRPF1B, 2 and 3, respectively). Also exhibits modest activity at BRD9 (Kd = 1130 nM). Exhibits selectivity for BRPF over 44 other bromodomains. Orally bioavailable. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 353.39 |
| 分子式 | C18H15N3O3 |
| 参考文献 | Igoeet al (2017) Design of a biased potent small molecule inhibitor of the bromodomain and PHD finger-containing (BRPF) proteins suitable for cellular and in vivo studies. J.Med.Chem. PMID: 28068087. |
