| 货号 | 2349/50 |
| 别名 | (2S,13bS)-2-Methoxy-2,3,5,6,8,9,10, |
| 供应商 | Tocris |
| 生物活性 | Competitive nicotinic acetylcholine receptor antagonist with moderate selectivity for the neuronal α4 receptor subunit (IC50 values are 0.19 and 0.37 μM for α4β4 and α4β2 receptors respectively). Antagonizes behavioral effects of nicotine in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 356.26 |
| 分子式 | C16H21NO3.HBr |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 25 mM in DMSO |
| CAS号 | 29734-68-7 |
| 参考文献 | Harveyet al (1996) Multiple determinants of dihydro-β-erythroidine sensitivity on rat neuronal nicotinic receptor #945; subunits. J.Neurochem. 67 1953. PMID: 8863500. Damajet al (1995) In vivo pharmacological effects of dihydro-β-erythroidine, a nicotinic antagonist, in mice. Psychopharmacology 117 67. PMID: 7724704. Williams and Robinson (1984) Binding of the nicotinic cholinergic antagonist, dihydro-β-erythroidine, to rat brain tissue. J.Neurosci. 4 2906. PMID: 6502210. |