| 货号 | 5144/50 |
| 别名 | 1-[(2-Chlorophenyl)methyl]-5'-phenyl |
| 供应商 | Tocris |
| 生物活性 | CARP-1 mimetic; interferes with CARP-1 binding to APC-2. Enhances CARP-1 expression and induces G2/M cell cycle arrest. Induces apoptosis and suppresses cell growth in cancer cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 405.9 |
| 分子式 | C22H16ClN3OS |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO |
| 参考文献 | Ashouret al (2013) CARP-1 functional mimetics: a novel class of small molecule inhibitors of medulloblastoma cell growth. PLoS ONE 8 e66733. PMID: 23826121. Puliyappadambaet al (2011) Antagonists of anaphase-promoting complex (APC)-2-cell cycle and apoptosis regulatory protein (CARP)-1 interaction are novel regulators of cell growth and apoptosis. J.Biol.Chem. 286 38000. PMID: 21903591. |