AZ 191 (50 MG)
货号：
5232/50 基本售价：
11084.4 元 规格：
50 mg
产品信息
概述| 货号 | 5232/50 |
| 别名 | N-[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-pyrimidinamine |
性能| 供应商 | Tocris |
| 生物活性 | Potent DYRK1B inhibitor (IC50 values are 17, 88 and 1890 nM for DYRK1B, DYRK1A and DYRK2 respectively). Inhibits DYRK1B-induced Gi phase cell cycle arrest in Panc-1 cells in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 429.52 |
| 分子式 | C24H27N7O |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
| 参考文献 | Ashfordet al (2014) A novel DYRK1B inhibitor AZ191 demonstrates that DYRK1B acts independently of GSK3 |
