AI-3 (50 MG)
货号：
5145/50 基本售价：
11084.4 元 规格：
50 mg
产品信息
概述| 货号 | 5145/50 |
| 别名 | 1-Chloro-6,7-dihydro-6,6-dimethyl-3-(methylsulfonyl)-benzo[c]thiophen-4(5H)-one |
性能| 供应商 | Tocris |
| 生物活性 | Antioxidant response element (ARE) activator; disrupts Nrf2/Keap1 and Keap1/Cul3 interactions and stabilizes Nrf2. Activates ARE in an Nrf2 and PI 3-kinase dependent manner. Induces cytoprotective gene expression in vitroandin vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 292.8 |
| 分子式 | C11H13ClO3S2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| 参考文献 | Wanget al (2013) In vitro and in vivo characterization of a tunable dual-reactivity probe of the Nrf2-ARE pathway. ACS Chem.Biol. 8 1764. PMID: 23773140. |
