| 货号 | 2901/50 |
| 别名 | 6-Chloro-2,3-dihydro-5-methyl-N-[6- |
| 供应商 | Tocris |
| 生物活性 | 5-HT2C receptor antagonist that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively. Also displays selectivity over a range of other 5-HT, dopamine and adrenergic receptors. Brain penetrant; exerts anxiolytic-like activity. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 467.78 |
| 分子式 | C21H19ClN4O2.2HCl |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO |
| CAS号 | 181632-25-7 |
| 参考文献 | Daltonet al (2006) Serotonin 1B and 2C receptor interactions in the modulation of feeding behaviour in the mouse. Psychopharmacology 185 45. PMID: 16470405. Bromidgeet al (1997) 6-Chloro-5-methyl-1-[[(2-methyl-3-pyridyl)oxy]-5-pyridyl]carbamoyl]-indoline (SB-242084): the first selective and brain penetrant 5-HT2C receptor antagonist. J.Med.Chem. 40 3494. PMID: 9357513. Kennetet al (1997) SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist. Neuropharmacology 36 609. PMID: 9225286. |