| 货号 | 9000341-5mg |
| 描述 | Diacylglycerols (DAG) are produced by the hydrolysis of membrane phospholipids. They act as lipid second messengers, activating PKC and regulating cell growth and apoptosis. They also serve as substrates for DAG kinases for the production of phosphatidic acid, another important lipid messenger. 1-NBD-decanoyl-2-decanoyl-sn-glycerol has the fluorophore nitrobenzoxadiazole (NBD) attached to the ω-end of the terminal decanoyl chain of the model DAG, 1,2-didecanoyl-sn-glycerol. Fluorescently-tagged lipids have been used to study their interactions with proteins,1 their utilization by cells and liposomes,2,3 and for the development of assays for lipid metabolism.4,5 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Kumagai, K.,Yasuda, S.,Okemoto, K., et al. CERT mediates intermembrane transfer of various molecular species of ceramides. The Journal of Biological Chemisty 280(8), 6488-6495 (2005). 2.Luo, M.,Jones, S.M.,Peters-Golden, M., et al. Nuclear localization of 5-lipoxygenase as a determinant of leukotriene B4 synthetic capacity. Proceedings of the National Academy of Sciences of the United States of America 100(21), 12165-12170 (2003). 3.Moreno, M.J.,Estronca, L.M.B.B., and Vaz, W.L.C. Translocation of phospholipids and dithionite permeability in liquid-ordered and liquid-disordered membranes. Biophysical Journal 91, 873-881 (2006). 4.Loidl, A.,Claus, R.,Deigner, H.P., et al. High-precision fluorescence assay for sphingomyelinase activity of isolated enzymes and cell lysates. Journal of Lipid Research 43, 815-823 (2002). 5.Tani, M.,Okino, N.,Mitsutake, S., et al. Specific and sensitive assay for alkaline and neutral ceramidases involving C12-NBD-ceramide. Journal of Biochemistry 125, 746-749 (1999). | |
| 运输条件 | Dry ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 纯度 | ≥98% |
| 计算分子量 | 578.7 |
| 分子式 | C29H46N4O8 |
| 稳定性 | ≥ 1 year |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |