4-Methylbenzylidene camphor
货号：
13840-10g 基本售价：
10976.0 元 规格：
10 g
产品信息
概述| 货号 | 13840-10g |
| 描述 | 4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations that also has estrogenic activities.1,2 It has estrogenic activity in fish and in mammals, binding competitively to estrogen receptors and stimulating transactivation.1 In addition to reducing receptor sensitivity to estradiol, 4-MBC directs dose-dependent changes in the expression of estrogen receptor subtypes, progesterone receptor, and androgen receptor.1,2 This results in changes in reproductive organ and brain development in both males and females.1,2 When applied topically, it is absorbed systemically and can be detected in urine.3 |
| 别名 | Enzacamene;Eusolex 6300;4-MBC;Neo Heliopan MBC;Parsol 500;Uvinul MBC 95; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Durrer, S.,Maerkel, K.,Schlumpf, M., et al. Estrogen target gene regulation and coactivator expression in rat uterus after developmental exposure to the ultraviolet filter 4-methylbenzylidene camphor. Endocrinology 146(5), 2130-2139 (2005).
2.Durrer, S.,Ehnes, C.,Fuetsch, M., et al. Estrogen sensitivity of target genes and expression of nuclear receptor co-regulators in rat prostate after pre- and postnatal exposure to the ultraviolet filter 4-methylbenzylidene camphor. Environmental Health Perspectives 115, 42-50 (2007).
3.Janjua, N.R.,Mogensen, B.,Andersson, A.M., et al. Systemic absorption of the sunscreens benzophenone-3, octyl-methoxycinnamate, and 3-(4-methyl-benzylidene) camphor after whole-body topical application and reproductive hormone levels in humans. Journal of Investigative Dermatology 123, 57-61 (2004).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 254.4 |
| 分子式 | C18H22O |
| CAS号 | 36861-47-9 |
| 稳定性 | ≥ 2 years |
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