Isopropyl dodec-11-enylfluorophosphonate
货号：
11613-10mg 基本售价：
10976.0 元 规格：
10 mg
产品信息
概述| 货号 | 11613-10mg |
| 描述 | Isopropyl dodec-11-enylfluorophosphonate is an organophosphorus ester that antagonizes the central cannabinoid (CB1) receptor and inhibits FAAH with similar potencies (IC50s = 2 nM).1,2 At 30 mg/kg, this compound inhibits 99% of the brain neuropathy target esterase-lysophospholipase, which is attributed to causing delayed toxicity in mice.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Segall, Y.,Quistad, G.B.,Sparks, S.E., et al. Toxicological and structural features of organophosphorus and organosulfur cannabinoid CB1 receptor ligands. Toxicological Sciences 76, 131-137 (2003).
2.Segall, Y.,Quistad, G.B., and Casida, J.E. Cannabinoid CB1 receptor chemical affinity probes: Methods suitable for preparation of isopropyl [11,12-3H]dodecylfluorophosphonate and [11,12-3H]dodecanesulfonyl fluoride. Synthetic Commun. 33(12), 2151-2159 (2003).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 292.4 |
| 分子式 | C15H30FO2P |
| CAS号 | 623114-64-7 |
| 稳定性 | ≥ 1 year |
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