| 货号 | 5983/50 |
| 别名 | 3,4,5,6,7,9-Hexahydro-3,3,6,6-tetra |
| 供应商 | Tocris |
| 生物活性 | Potentδ-opioid receptor positive allosteric modulator (EC50 = 30 nM). Exhibits 100-fold selectivity for δoverμ-opioid receptor. Enhances affinity of [Leu5]-Enkephalin (Cat.No. 1889), SNC 80 (Cat.No. 0764) and TAN 67 (Cat.No. 0921) for the δ-opioid receptor. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 470.61 |
| 分子式 | C31H34O4 |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO |
| 参考文献 | Shanget al (2016) Proposed mode of binding and action of positive allosteric modulators at opioid receptors. ACS Chem.Biol. 11 1220. PMID: 26841170. Burfordet al (2015) Discovery, synthesis, and molecular pharmacology of selective positive allosteric modulators of the δ-opioid receptor. J.Med.Chem. 58 4220. PMID: 25901762. |