货号 | 63180-10mg |
描述 | Dimethylallyl pyrophosphate and isopentyl pyrophosphate undergo condensation to yield geranyl pyrophosphate, which undergoes condensation with a second molecule of isopentyl pyrophosphate to yield farnesyl pyrophosphate.1,2 Farnesylation is essential for the function of a number of proteins involved in signal transduction.3,4 |
别名 | Dimethylallyl Pyrophosphate; |
供应商 | Cayman |
应用文献 | |
1.Barnard, G.F., and Popják, G. Human liver prenyltransferase and its characterization. Biochimica et Biophysica Acta 661, 87-99 (1981). 2.Laskovics, F.M., and Poulter, C.D. Prenyltransferase: Determination of the binding mechanism and individual kinetic constants for farnesylpyrophosphate synthetase by rapid quench and isotope partitioning experiments. Biochemistry 20, 1893-1901 (1981). 3.Hohl, R.J.,Lewis, K.A.,Cermak, D.M., et al. Stereochemistry-dependent inhibition of Ras farnesylation by farnesylphosphonic acids. Lipids 33, 39-46 (1998). 4.Rando, R.R. Chemical biology of protein isoprenylation/methylation. Biochimica et Biophysica Acta 1300, 5-16 (1996). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 300.2 |
分子式 | C5H12O7P2 • 3(NH4) |
CAS号 | 1186-30-7 |
稳定性 | ≥ 1 year |
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