| 货号 | 21216-5g |
| 描述 | Tiamulin is a pleuromutilin antibiotic that binds to peptidyl transferase in the 50S ribosomal subunit.1,2 It has been used in veterinary medicine to treat enteric diseases and enzootic pneumonia.2,3 Tiamulin is effective against mycoplasmas and Gram-positive bacteria.4,5 |
| 别名 | 81723 Hfu;SQ 22,947; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Long, K.S.,Hansen, L.H.,Jakobsen, L., et al. Interaction of pleuromutilin derivatives with the ribosomal peptidyl transferase center. Antimicrob. Agents and Chemother. 50(4), 1458-1462 (2006). 2.Poulsen, S.M.,Karlsson, M.,Johansson, L.B., et al. The pleuromutilin drugs tiamulin and valnemulin bind to the RNA at the peptidyl transferase centre on the ribosome. Mol.Microbiol. 41(5), 1091-1099 (2001). 3.Kilaru, S.,Collins, C.M.,Hartley, A.J., et al. Establishing molecular tools for genetic manipulation of the pleuromutilin-producing fungus Clitopilus passeckerianus. Appl. Environ. Microbiol. 75(22), 7196-7204 (2009). 4.Hannan, P.C.T.,Windsor, G.D.,de Jong, A., et al. Comparative susceptibilities of various animal-pathogenic mycoplasmas to fluoroquinolones. Antimicrob. Agents Chemother. 41(9), 2037-2040 (1997). 5.Wilson, D.N. The A-Z of bacterial translation inhibitors. Crit. Rev. Biochem. Mol. Biol. 44(6), 393-433 (2009). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 22 |
| 纯度 | ≥95% |
| 计算分子量 | 609.8 |
| 分子式 | C28H47NO4S • C4H4O4 |
| CAS号 | 55297-96-6 |
| 稳定性 | ≥ 2 years |
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