Δ17-U-46619
货号：
16460-1mg 基本售价：
10780.0 元 规格：
1 mg
产品信息
概述| 货号 | 16460-1mg |
| 描述 | U-46619 is the consensus stable analog of prostaglandin H2/thromboxane A2(PGH2/TXA2) and has been used as a TXA2 agonist in pharmacologic studies for several decades.1 There have been several hypotheses put forward by scientists studying ω-3 fatty acids stipulating that the agonist activity of TXA3 was substantially different than that of TXA2.2 However, no stable analogs of TXA3 were available to test these theories. Δ17-U-46619 is the first direct, stable analog of TXA3 ever synthesized. There are no published reports on its activity to date. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Bundy, G.L. The synthesis of prostaglandin endoperoxide analogs. Tetrahedron Letters 24, 1957-1960 (1975).
2.Parent, C.A.,Lagarde, M.,Venton, D.L., et al. Selective modulation of the human platelet thromboxane A2/prostaglandin H2 receptor by eicosapentaenoic and docosahexaenoic acids in intact platelets and solubilized platelet membranes. The Journal of Biological Chemisty 267, 6541-6547 (1992).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 348.5 |
| 分子式 | C21H32O4 |
| CAS号 | 946602-01-3 |
| 稳定性 | ≥ 2 years |
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