VEGFR2 Kinase Inhibitor I
货号：
13578-10mg 基本售价：
10780.0 元 规格：
10 mg
产品信息
概述| 货号 | 13578-10mg |
| 描述 | Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D. VEGFR2 kinase inhibitor I is a potent, cell-permeable inhibitor of mouse VEGFR2 kinase (IC50 = 70 nM).1 It has little or no effect against receptors for platelet-derived growth factor, epidermal growth factor, or insulin-like growth factor (IC50 > 100 µM).1 |
| 别名 | SU 5408; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Sun, L.,Tran, N.,Tang, F., et al. Synthesis and biological evaluations of 3-substituted indolin-2-ones: A novel class of tyrosine kinase inhibitors that exhibit selectivity toward particular receptor tyrosine kinases. Journal of Medicinal Chemistry 41(14), 2588-2603 (1998).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 310.4 |
| 分子式 | C18H18N2O3 |
| CAS号 | 15966-93-5 |
| 稳定性 | ≥ 2 years |
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