1.Cox, B.,Murphey, L.J.,Zackert, W.E., et al. Human colorectal cancer cells efficiently conjugate the cyclopentenone prostaglandin, prostaglandin J2, to glutathione. Biochimica et Biophysica Acta 1584, 37-45 (2002). 2.Brunoldi, E.M.,Zanoni, G.,Vidari, G., et al. Cyclopentenone prostaglandin, 15-deoxy-Δ12,14-PGJ2, is metabolized by HepG2 cells via conjugation with glutathione. Chemical Research in Toxicology 20, 1528-1535 (2007). 3.Paumi, C.M.,Smitherman, P.K.,Townsend, A.J., et al. Glutathione S-transferases (GSTs) inhibit transcriptional activation by the peroxisomal proliferator-activated receptor γ (PPARγ) ligand, 15-deoxy-Δ12,14 prostaglandin J2(15-d-PGJ2).. Biochemistry 43(8), 2345-2352 (2004).
|