rac-7-methoxy Propranolol
货号：
17576-10mg 基本售价：
10640.0 元 规格：
10 mg
产品信息
概述| 货号 | 17576-10mg |
| 描述 | Propranolol, one of the first β-blockers used in cardiovascular medicine, inhibits β1-, β2-, and β3-adrenergic receptors with log KD values of -8.16, -9.08, and -6.93, respectively.1,2 Ring-hydroxylated isomers of propranolol also antagonize β-adrenergic receptors and demonstrate potent vasodilator activity.3rac-7-methoxy Propranolol is an intermediate for the preparation of rac-7-hydroxy propranolol. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Baker, J.G. The selectivity of β-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptors. Br. J. Pharmacol. 144(3), 317-322 (2005).
2.Mehvar, R., and Brocks, D.R. Stereospecific pharmacokinetics and pharmacodynamics of β-adrenergic blockers in humans. J. Pharm. Pharm. Sci. 4(2), 185-200 (2001).
3.Oatis, J.E., Jr.,Russell, M.P.,Knapp, D.R., et al. Ring-hydroxylated propranolol: Synthesis and β-receptor antagonist and vasodilating activities of the seven isomers. J. Med. Chem. 24(3), 309-314 (1981).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 289.4 |
| 分子式 | C17H23NO3 |
| CAS号 | 76275-53-1 |
| 稳定性 | ≥ 2 years |
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